Exciting news for patients! Xiidra has the BEST* insurance coverage for any branded dry eye prescription product across Commercial and Medicare prescription plans!
*Based on MMIT data from February 2025. Up to 94% of commercial and 70% of Medicare Part D patients may be covered.
Xiidra reduces both dry eye symptoms (what you can feel) and signs† (what your doctor can see).
†Xiidra may provide lasting symptom relief for some patients with continued twice-daily use. In clinical studies, Xiidra reduced symptoms of eye dryness at 2 weeks in 2 out of 4 studies, with improvements observed at 6 and 12 weeks in all 4 studies.
Eligible patients with commercial insurance may pay as little as $0 for Xiidra with a Xiidra Savings Card.‡ Click the button below to get started.
‡Offer not valid for patients whose prescriptions are reimbursed by any federal or state healthcare program, including Medicaid, Medicare, TRICARE, or any other federal or state healthcare program. Other restrictions apply. See complete Eligibility Criteria and Terms and Conditions.
Check out our in depth FAQ and find out more!
Dry Eye QuizAre over-the-counter drops just hitting "pause" on your symptoms? Inflammation could be at the root of the problem. Take the quiz and discuss the results with your doctor.
Take the Dry Eye Quiz
Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.
Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.
The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.
To help avoid eye injury or contamination of the solution, do not touch the container tip to your eye or any surface. If you wear contact lenses, remove them before using Xiidra and wait for at least 15 minutes before placing them back in your eyes.
It is not known if Xiidra is safe and effective in children under 17 years of age.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
For additional safety information, click here for Full Prescribing Information and Patient Information and discuss with your doctor.
Follow XIIDRA®: 
Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.
Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.
The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.
