Remember: patience is key. Here's what you may expect for
Xiidra's treatment timeline.

Time To Efficacy


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Learn more about how prescription Xiidra works and when you may anticipate symptom relief.

If you recently started using prescription Xiidra you may be wondering how long it takes to potentially feel symptom relief.

Everyone's dry eye journey may be different, but one thing to keep in mind is that it may not happen overnight. Dry eye disease is chronic and may progress over time.

While some of us are accustomed to getting what we want instantly, treating both the signs and symptoms of dry eye disease and feeling symptom relief can take time.

First, it's important to think about the different factors that may lead to dry eye disease.

There are several proposed factors that can cause stress to your eyes including prolonged screen time, low humidity and reading a lot. This kind of stress can cause increased tear evaporation, which can lead to inflammation on the surface of your eyes, causing more stress. The cycle can go on and on.

Scientists believe that inflammation on the surface of the eye may be a factor in causing dry eye. Inflammation is typically an immune system response to stress, irritation, bacteria, toxins, or a number of other causes.

A common first step for treating dry eye disease symptoms is to use over-the-counter eye drops*, which work by lubricating the surface of the eye. For some, using over-the-counter eye drops alone don't cut it, so the next step would be to visit an eye doctor who will decide what next steps are best to take. They might prescribe a treatment like Xiidra.

Twice-daily Xiidra targets a source of inflammation in the eye that can cause dry eye disease.


As you use Xiidra, it's important to continue the prescribed dosage. In clinical studies, Xiidra was shown to provide relief of symptoms of eye dryness for some patients in as little as 2 weeks of use. Many patients observed improvements in symptoms at 6 weeks or 12 weeks. We can't say exactly where along that timeline you may notice a difference, or if Xiidra will work for you, but it's important to follow your doctor's treatment recommendations.

Consider setting up touch points with your doctor and discuss the most appropriate timing of follow-up. By then, you may have noticed some relief, but your doctor can also help you determine how well your eyes are responding to Xiidra and how to proceed with treatment prescribed by your doctor.

*Over-the-counter eye drops = artificial tears.

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What is Xiidra?

Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.

Important Safety Information

Do not use Xiidra if you are allergic to any of its ingredients. Seek medical care immediately if you get any symptoms of an allergic reaction.

The most common side effects of Xiidra include eye irritation, discomfort or blurred vision when the drops are applied to the eyes, and an unusual taste sensation.

To help avoid eye injury or contamination of the solution, do not touch the container tip to your eye or any surface. If you wear contact lenses, remove them before using Xiidra and wait for at least 15 minutes before placing them back in your eyes.

It is not known if Xiidra is safe and effective in children under 17 years of age.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

What is Xiidra?

Xiidra (lifitegrast ophthalmic solution) 5% is a prescription eye drop used to treat the signs and symptoms of dry eye disease.

For additional safety information, click here for Full Prescribing Information and Patient Information and discuss with your doctor.

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